ROULEAUX Meaning and
Definition
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Rouleaux is a term typically used in the field of hematology and refers to the phenomenon observed during blood smears or microscopic examination of blood cells. It describes the abnormal aggregation or clustering of red blood cells (RBCs), giving them a stacked or coin-like appearance resembling a stack of poker chips or rolls of coins. This condition is caused by the presence of specific proteins or molecules on the surface of RBCs that promote their adhesion or sticking together.
Rouleaux formation can occur due to various factors, such as increased levels of fibrinogen, globulins, or other proteins in the blood, as well as certain medical conditions like multiple myeloma, Waldenstrom macroglobulinemia, or chronic inflammation. Additionally, some medications can induce rouleaux formation as a side effect.
The presence of rouleaux is of clinical significance as it can affect blood flow and circulation. The stacking of red blood cells hampers their ability to flow smoothly through narrow blood vessels, potentially leading to impaired oxygen delivery to tissues and organs. In a laboratory setting, observing rouleaux formation in a blood smear can be an important clue in diagnosing and monitoring certain diseases, particularly those associated with excessive protein production.
Laboratory technicians and hematologists often examine blood smears under a microscope to assess the extent and appearance of rouleaux formation, which aids in the evaluation and management of various medical conditions. Managing rouleaux formation may involve treating the underlying cause, such as treating the underlying disease or adjusting medication dosage, to restore normal blood flow and prevent potential complications.
Common Misspellings for ROULEAUX
Etymology of ROULEAUX
The word "rouleaux" comes from the French language and is the plural form of "rouleau", which means "roll" or "scroll" in English. It ultimately originates from the Old French word "rolle", which has the same meaning. The term "rouleaux" is commonly used in various contexts, such as art, fashion, and medicine, to refer to small cylindrical rolls or tubes.
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