POLYGENIC DISEASE Meaning and
Definition
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A polygenic disease is a type of disease or disorder that is influenced by multiple genes. It is characterized by the involvement of various genetic factors rather than being caused by a single gene mutation. In contrast to monogenic diseases, which are caused by mutations in a single gene, polygenic diseases arise due to the combined effects of multiple genetic variations that interact with each other and with environmental factors.
Polygenic diseases exhibit a complex inheritance pattern, meaning that their onset and severity are determined by the interaction of multiple genetic and environmental factors. These diseases often have a multifactorial etiology, meaning that both genetic predisposition and environmental factors contribute to their development. Examples of polygenic diseases include type 2 diabetes, hypertension, obesity, heart disease, certain forms of cancer, and psychiatric disorders such as schizophrenia and bipolar disorder.
Because polygenic diseases involve multiple genes and interactions between various genetic and environmental factors, their genetic inheritance patterns are more challenging to understand and predict. Genome-wide association studies (GWAS) are commonly conducted to identify specific genetic variations associated with polygenic diseases, but the exact mechanisms and interactions involved in their development are still being researched. Understanding the genetic basis of polygenic diseases can provide valuable insights into their pathogenesis, diagnosis, and potential treatment options.
Common Misspellings for POLYGENIC DISEASE
- oolygenic disease
- lolygenic disease
- -olygenic disease
- 0olygenic disease
- pilygenic disease
- pklygenic disease
- pllygenic disease
- pplygenic disease
- p0lygenic disease
- p9lygenic disease
- pokygenic disease
- popygenic disease
- pooygenic disease
- poltgenic disease
- polggenic disease
- polhgenic disease
- polugenic disease
- pol7genic disease
- pol6genic disease
Etymology of POLYGENIC DISEASE
The word "polygenic" is derived from two Greek roots: "poly" meaning "many" and "genic" meaning "producing" or "caused by".
The term "polygenic" refers to traits or diseases that are influenced by multiple genes, meaning that the condition is caused by the combined effect of multiple genetic variants rather than being determined by a single gene.
So, the word "polygenic disease" can be understood as a disease influenced by the interaction of multiple genes.
Similar spelling word for POLYGENIC DISEASE
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