LTB RECEPTORS Meaning and
Definition
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LTB receptors, also known as leukotriene B receptors, are a specific type of cell surface receptors that are found in various tissues throughout the body. These receptors are involved in mediating the actions of leukotriene B, a type of inflammatory lipid mediator that plays a crucial role in the immune response.
LTB receptors belong to the G protein-coupled receptor (GPCR) superfamily, which are a large group of membrane receptors involved in diverse physiological processes. There are two known subtypes of LTB receptors, LTB1 and LTB2, which are encoded by different genes and exhibit distinct tissue distribution and signaling pathways.
When leukotriene B is released or synthesized in response to an inflammatory stimulus, it can bind to LTB receptors on target cells, initiating a cascade of intracellular signaling events. Activation of LTB receptors can trigger a range of cellular responses, including inflammation, smooth muscle contraction, immune cell recruitment, and vascular permeability.
The binding of leukotriene B to LTB receptors is crucial for the recruitment and activation of immune cells, such as neutrophils and eosinophils, which play a significant role in the pathogenesis of various inflammatory diseases, including asthma and rheumatoid arthritis. Therefore, LTB receptors have emerged as a potential therapeutic target for the treatment of these conditions.
In summary, LTB receptors are cell surface receptors that mediate the actions of leukotriene B, a lipid mediator involved in inflammation and immune response. Targeting LTB receptors may hold therapeutic potential for various inflammatory diseases.
Common Misspellings for LTB RECEPTORS
- ktb receptors
- ptb receptors
- otb receptors
- lrb receptors
- lfb receptors
- lgb receptors
- lyb receptors
- l6b receptors
- l5b receptors
- ltv receptors
- ltn receptors
- lth receptors
- ltg receptors
- ltb eeceptors
- ltb deceptors
- ltb feceptors
- ltb teceptors
- ltb 5eceptors
- ltb 4eceptors
- ltb rwceptors
Etymology of LTB RECEPTORS
The term "LTB receptors" is an abbreviation for "leukotriene B receptors". The etymology of this term can be broken down as follows:
1. Leukotriene: The word "leukotriene" is derived from the Greek words "leukos", meaning "white", and "treis", meaning "three". It was coined in 1938 to describe a class of bioactive lipid mediators derived from arachidonic acid, which were initially found in leukocytes (white blood cells).
2. B: The letter "B" in "LTB" represents a specific subclass of leukotrienes, namely leukotriene B. Leukotrienes are subdivided into groups A, B, C, D, and E, with each group referring to different chemical structures and biological activities.
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