LANGERHANS Meaning and
Definition
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Langerhans refers to a specialized group of cells found in the pancreas, particularly in the islets of Langerhans. These islets are small clusters of cells scattered throughout the pancreas and are responsible for producing and releasing important hormones, such as insulin, glucagon, and somatostatin, into the bloodstream. Langerhans cells are named after the German physician Paul Langerhans who first discovered them in 1869.
These cells play a crucial role in regulating blood sugar levels and maintaining overall glucose balance in the body. Insulin, produced by the beta cells in the islets of Langerhans, helps to lower blood sugar levels by facilitating the uptake of glucose from the bloodstream into cells and promoting its storage as glycogen in the liver and muscle tissues. On the other hand, glucagon, produced by the alpha cells in the islets, acts to raise blood sugar levels by stimulating the liver to convert stored glycogen into glucose and releasing it into the bloodstream.
Aside from their endocrine function, Langerhans cells also have an immunological role. They function as antigen-presenting cells in the immune system, playing a vital role in the detection and response to foreign substances, such as bacteria and viruses. Langerhans cells are commonly found in the skin, where they help protect the body from infections and play a key role in the initiation of immune responses.
Common Misspellings for LANGERHANS
Etymology of LANGERHANS
The word "Langerhans" is derived from the last name of the German physician Paul Langerhans. Paul Langerhans (1847-1888) was a German pathologist who is known for the discovery of the islets of Langerhans in the pancreas, which are responsible for producing insulin. These islets were named after him as a tribute to his groundbreaking work in the field of medical research. Thus, the term "Langerhans" is eponymous, originating from the name of the scientist who made the discovery.
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