How Do You Spell HYPERPLASTIC CHONDRODYSTROPHY?

1. Hyperplastic chondrodystrophy is a rare genetic disorder characterized by an abnormal growth of cartilage, leading to skeletal deformities and short stature. The condition primarily affects the long bones, particularly the legs, resulting in a disproportionate limb length and joint abnormalities.

   The term "hyperplastic" refers to an excessive proliferation of cells in the cartilaginous tissue, which leads to an abnormal increase in the size of the affected bones. This excessive growth disrupts the proper development and structure of the skeletal system, resulting in shortened limbs and other deformities.

   Chondrodystrophy, on the other hand, refers to a condition where the growth and development of cartilage are disturbed, leading to skeletal abnormalities. In hyperplastic chondrodystrophy, the cartilage cells experience abnormal proliferation and fail to differentiate into bone cells properly. This results in disturbed bone growth and development.

   The symptoms of hyperplastic chondrodystrophy typically manifest during childhood, with affected individuals often having shorter limbs and a disproportionate body height. Other common features include joint deformities, such as bowed legs or knock knees, as well as a curved spine. These skeletal abnormalities can cause mobility issues and potentially impact an individual's quality of life.

   The underlying cause of hyperplastic chondrodystrophy is a mutation in specific genes involved in cartilage and bone development. However, the condition can vary in severity among affected individuals, with some experiencing milder symptoms than others. Treatment options for hyperplastic chondrodystrophy primarily focus on managing symptoms and improving mobility through the use of orthopedic interventions, physical therapy, and supportive care.

2. A form in which there is an extreme outgrowth of the epiphyses with corresponding distortion of the joints.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for HYPERPLASTIC CHONDRODYSTROPHY

The word "hyperplastic chondrodystrophy" is a medical term that combines three parts: "hyperplastic", "chondro", and "dystrophy".

1. "Hyperplastic" is derived from the Greek word "hyper", meaning "over" or "above", and "plasis", meaning "formation" or "development". It refers to an abnormal increase in the number of cells within tissues or organs.

2. "Chondro" is derived from the Greek word "chondros", which means "cartilage". It refers to the tissue type found in joints, the rib cage, the ear, and other areas of the body.

3. "Dystrophy" comes from the Greek word "dys", meaning "abnormal" or "faulty", and "trophe", meaning "nourishment" or "development".