FIBRINOKINASE Meaning and
Definition
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Fibrinokinase, also known as plasminogen activator, is an enzyme that plays a crucial role in the clotting process within the human body. It is a proteolytic enzyme that catalyzes the conversion of plasminogen, an inactive precursor protein, into plasmin, an active serine protease. Plasminogen activators are responsible for initiating the breakdown of fibrin, a protein that forms the structural framework of blood clots, ultimately leading to their dissolution.
Fibrinokinase is involved in the mechanism of fibrinolysis, which is the natural breakdown of blood clots. When a blood clot is formed in response to an injury or to prevent excessive bleeding, the activation of fibrinokinase is necessary to initiate the process of clot dissolution. Fibrinokinase acts by cleaving the plasminogen molecule into smaller fragments, thereby generating plasmin. Plasmin then functions to degrade fibrin strands within the clot, resulting in its dissolution and clearance.
Fibrinokinase is essential for maintaining normal blood clotting and preventing pathological clot formation. It is often utilized in medical interventions, such as thrombolytic therapy, where exogenous fibrinokinase or plasminogen activators are administered to patients to break down blood clots in conditions like myocardial infarction, stroke, or pulmonary embolism.
The discovery and development of fibrinokinase-based therapies have substantially revolutionized the management of clot-related diseases, providing alternative interventions to surgical procedures. Furthermore, the study of fibrinokinase and its interaction with other components of the clotting system plays a crucial role in enhancing our understanding of blood disorders and improving treatment strategies.
Common Misspellings for FIBRINOKINASE
- dibrinokinase
- cibrinokinase
- vibrinokinase
- gibrinokinase
- tibrinokinase
- ribrinokinase
- fubrinokinase
- fjbrinokinase
- fkbrinokinase
- fobrinokinase
- f9brinokinase
- f8brinokinase
- fivrinokinase
- finrinokinase
- fihrinokinase
- figrinokinase
- fibeinokinase
- fibdinokinase
- fibfinokinase
- fibtinokinase
Etymology of FIBRINOKINASE
The word "fibrinokinase" is derived from the combination of two main components: "fibrin" and "kinase".
- "Fibrin" refers to a protein involved in blood clot formation. It is derived from the Latin word "fibra", which means "fiber". The word "fibrin" was coined in the mid-19th century by German anatomist and physiologist Robert Virchow.
- "Kinase" is a term used for a class of enzymes that catalyze the transfer of a phosphate group from ATP (adenosine triphosphate) to another molecule via phosphorylation. The term "kinase" is derived from the Greek word "kinēsis", meaning "movement" or "motion", combined with the suffix "-ase", which denotes an enzyme. The word "kinase" was first introduced in the early 20th century.
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