ERYTHROID BURST FORMING UNIT Meaning and
Definition
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Erythroid Burst Forming Unit (BFU-E) is a term used in the field of hematology and refers to a specific type of progenitor cell that is responsible for the production and maturation of red blood cells, also known as erythrocytes.
The term "erythroid" refers to anything related to red blood cells, while "burst forming unit" indicates the ability of the cell to give rise to a colony of cells when cultured under specific conditions. BFU-Es are considered to be more primitive and less mature than erythroid colony forming units (CFU-Es), another type of progenitor cell that also gives rise to red blood cells.
BFU-Es are derived from hematopoietic stem cells, which are present in the bone marrow and have the ability to differentiate into various types of blood cells. When stimulated by certain growth factors such as erythropoietin, which is produced by the kidneys in response to low oxygen levels in the blood, BFU-Es undergo a series of division and differentiation steps to produce a large number of erythrocytes. These mature red blood cells are then released into the bloodstream, where they function to transport oxygen to various tissues and organs throughout the body.
Studying BFU-Es and their regulation can provide important insights into the process of erythropoiesis, or red blood cell production, and may have implications for understanding and treating disorders associated with abnormal erythroid development and function.
Common Misspellings for ERYTHROID BURST FORMING UNIT
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