ENDOTHELIOLYSIN Meaning and
Definition
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Endotheliolysin is a term used in the field of medicine and biology, specifically in the study of endothelial cells and their functions. Endotheliolysin refers to any substance or enzyme that is capable of causing lysis or destruction of endothelial cells.
Endothelial cells are a type of specialized cells that line the inner walls of blood vessels and lymphatic vessels, forming a crucial barrier between the circulating blood or lymph and the surrounding tissues. These cells play a vital role in maintaining vascular integrity, regulating blood flow, and preventing the leakage of fluid and cells from blood vessels. Endotheliolysin disrupts this essential function by inducing the destruction of endothelial cells.
The role of endotheliolysins can be observed in various pathological conditions such as inflammation, infection, and certain autoimmune disorders. Certain bacteria, viruses, toxins, or immune system components can produce endotheliolysin or activate the release of endotheliolysin from immune cells, leading to the breakdown of endothelial cells. This can result in compromised vascular integrity, increased permeability, disruption of blood flow, and tissue damage.
Understanding the mechanisms of endotheliolysin-induced endothelial cell lysis is critical for understanding the pathophysiology of several cardiovascular diseases, sepsis, and organ dysfunction. Researchers often study endotheliolysins to gain insights into the underlying mechanisms of these disorders and develop potential therapeutic interventions to combat them.
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A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for ENDOTHELIOLYSIN
- wndotheliolysin
- sndotheliolysin
- dndotheliolysin
- rndotheliolysin
- 4ndotheliolysin
- 3ndotheliolysin
- ebdotheliolysin
- emdotheliolysin
- ejdotheliolysin
- ehdotheliolysin
- ensotheliolysin
- enxotheliolysin
- encotheliolysin
- enfotheliolysin
- enrotheliolysin
- eneotheliolysin
- enditheliolysin
- endktheliolysin
- endltheliolysin
- endptheliolysin
Etymology of ENDOTHELIOLYSIN
The word "endotheliolysin" is derived from the combination of three components: "endothelio", "lysis", and "in".
1. "Endothelio" is derived from the word "endothelium", which refers to the thin layer of cells lining the interior surface of blood vessels, lymphatic vessels, and the heart. "Endothelium" comes from the Greek words "endon", meaning "inside", and "thēlion", meaning "tissue".
2. "Lysis" comes from the Greek word "lusis", which means "a loosening" or "dissolving". It is often used to describe the destruction or disintegration of cells.
3. The suffix "-in" is often used to form nouns or adjectives denoting a substance or product, as well as indicating that it has a certain function or effect.
