COLIPASE B Meaning and
Definition
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Colipase B is a protein that plays a crucial role in the digestion and absorption of dietary fats within the human body. It is secreted by the pancreas and acts as a cofactor in the breakdown of triglycerides, which are the main form of fat in the diet.
The primary function of colipase B is to enhance the activity of pancreatic lipase, an enzyme that is responsible for the hydrolysis of triglycerides. Colipase B binds to the surface of lipid droplets and assists in the breakdown of fats by enabling the interaction between pancreatic lipase and its substrate. This interaction is particularly important in the small intestine, where most fat digestion takes place.
Colipase B contains a hydrophobic domain that allows it to anchor onto lipid droplets, and a flexible hinge region that facilitates the binding of pancreatic lipase. By forming a stable complex with pancreatic lipase, colipase B allows for efficient fat digestion and subsequent absorption of fatty acids and monoacylglycerols by the intestinal cells.
It is worth noting that colipase B is a variant of colipase A, a similar protein found in non-primates. Colipase B has distinct structural and functional characteristics compared to colipase A, making it specific to certain species, including humans. The presence of colipase B deficiency or dysfunction can significantly impair fat digestion and absorption, leading to malabsorption and related health conditions.
Common Misspellings for COLIPASE B
- xolipase b
- volipase b
- folipase b
- dolipase b
- cilipase b
- cklipase b
- cllipase b
- cplipase b
- c0lipase b
- c9lipase b
- cokipase b
- copipase b
- cooipase b
- colupase b
- coljpase b
- colkpase b
- colopase b
- col9pase b
- col8pase b
- colioase b
Etymology of COLIPASE B
The word "Colipase B" has relatively straightforward etymology.
"Colipase" is derived from the combination of two words: "colic" and "lipase".
- "Colic" comes from the Greek word "kolikos", which means "pertaining to the colon" or "relating to the colon". It is used to refer to conditions or pains related to the colon.
- "Lipase" comes from the Greek word "lipos", which means "fat". Lipases are enzymes that help break down fats or lipids into smaller molecules.
"B" is simply a designation or identifier used to distinguish Colipase B from other forms or variants of colipase.
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