CHOLECYSTOKININ TETRAPEPTIDE Meaning and
Definition
-
Cholecystokinin tetrapeptide (CCK-4) is a neuropeptide that acts as a potent agonist for the cholecystokinin receptor in the central nervous system. It is a short peptide consisting of four amino acids: phenylalanine, tryptophan, methionine, and arginine. CCK-4 is derived from the larger peptide hormone cholecystokinin (CCK) but possesses higher affinity and specificity for the CCK-B receptor subtype.
CCK-4 plays a crucial role in regulating various physiological processes, including the modulation of anxiety and panic responses. When CCK-4 is administered intravenously or via inhalation, it triggers rapid and intense anxiety symptoms, such as palpitations, shortness of breath, fear, and derealization, mimicking panic attacks in individuals susceptible to anxiety disorders.
Research suggests that CCK-4-induced panic attacks are mediated through the interaction with CCK-B receptors in the amygdala, a brain region involved in fear and anxiety responses. Due to its ability to induce panic-like symptoms, CCK-4 is widely used in experimental models to study panic disorder, anxiety, and the underlying neurobiological mechanisms.
In clinical settings, CCK-4 challenges may be utilized to provoke panic attacks in individuals with panic disorder, aiding in diagnosis and treatment planning. Additionally, CCK-4 has been investigated as a potential therapeutic target for anxiety disorders, and research is ongoing to explore the utility of CCK-B receptor antagonists in the management of panic disorder and related conditions.
Common Misspellings for CHOLECYSTOKININ TETRAPEPTIDE
- xholecystokinin tetrapeptide
- vholecystokinin tetrapeptide
- fholecystokinin tetrapeptide
- dholecystokinin tetrapeptide
- cgolecystokinin tetrapeptide
- cbolecystokinin tetrapeptide
- cnolecystokinin tetrapeptide
- cjolecystokinin tetrapeptide
- cuolecystokinin tetrapeptide
- cyolecystokinin tetrapeptide
- chilecystokinin tetrapeptide
- chklecystokinin tetrapeptide
- chllecystokinin tetrapeptide
- chplecystokinin tetrapeptide
- ch0lecystokinin tetrapeptide
- ch9lecystokinin tetrapeptide
- chokecystokinin tetrapeptide
- chopecystokinin tetrapeptide
- chooecystokinin tetrapeptide
- cholwcystokinin tetrapeptide
Etymology of CHOLECYSTOKININ TETRAPEPTIDE
The word "Cholecystokinin Tetrapeptide" has its etymology rooted in the scientific naming conventions for peptides and hormones.
- Cholecystokinin (CCK): The term "cholecystokinin" comes from the Greek words "chole" meaning "bile" and "cystokinin" meaning "gall bladder mover". This hormone was initially discovered in the gastrointestinal tract, specifically in the duodenum and jejunum, where it stimulates the release of bile from the gallbladder.
- Tetrapeptide: "Tetra-" comes from the Greek word "tetra", meaning "four", while "peptide" is derived from the Greek word "peptos", meaning "digested". A tetrapeptide refers to a peptide consisting of four amino acids.
Infographic
Add the infographic to your website:
