How Do You Spell BIOTINYLATION?

Pronunciation: [bˌa͡ɪə͡ʊtˌɪnɪlˈe͡ɪʃən] (IPA)

Biotinylation refers to the process of attaching a biotin molecule to a protein or other molecule. The spelling of this word can be explained through the use of IPA phonetic transcription. The first syllable, "bio," is pronounced as /baɪoʊ/, while the second syllable, "tinyl," is pronounced as /tɪ̃nɪl/. Finally, the ending "-ation" is pronounced as /-eɪʃən/. When combined, the word is spelled as "by-oh-tin-uh-ley-shuhn." This process of attaching biotin to molecules is commonly used in various research fields, including molecular biology and biochemistry.

Meaning and Definition
Common Misspellings
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BIOTINYLATION Meaning and Definition

  1. Biotinylation is a chemical process in which a biotin molecule is covalently attached to a target molecule, such as a protein or DNA, through a specific chemical reaction. Biotin, also known as vitamin B7, is a small molecule that is naturally occurring and essential for various biological processes in organisms.

    The covalent attachment of biotin to a target molecule through biotinylation enables the specific recognition and capture of the target in various biological and biomedical applications. Biotin has a high affinity for avidin and streptavidin, proteins found in many organisms, which can bind to biotin with exceptional strength and specificity. By incorporating biotin on a target molecule, it allows for the subsequent attachment of avidin or streptavidin, which can then be utilized for various purposes, such as detection, purification, or immobilization of the target molecule.

    Biotinylation methods can vary depending on the target molecule and the desired application. Common techniques for biotinylation include the use of biotin derivatives, such as N-hydroxysuccinimide (NHS) esters or maleimides, which react with specific functional groups on the target molecule (for example, primary amines or sulfhydryl groups). These reactions result in the stable attachment of a biotin molecule to the target, allowing for subsequent interactions with avidin or streptavidin.

    Overall, biotinylation is a powerful tool in various fields of biology and biotechnology, providing a means to specifically label, capture, or manipulate target molecules through their interaction with avidin or streptavidin.

Common Misspellings for BIOTINYLATION

Etymology of BIOTINYLATION

The word "biotinylation" is derived from the term "biotin", which itself originates from the German word "biotin" or "bios", meaning "life" in Greek. Biotin is a vitamin that plays a crucial role in various biochemical processes in living organisms. When biotin is conjugated or linked to another molecule, such as a protein or nucleic acid, it is referred to as biotinylation.

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Correct spelling for Biotinylation
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