ANTIONCOGENE Meaning and
Definition
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An antioncogene, also known as a tumor suppressor gene, is a specific gene that encodes proteins responsible for regulating cell growth and division, and thus preventing the formation and development of tumors. These genes act as control mechanisms within cells to ensure that they grow and divide at an appropriate rate and time.
The role of antioncogenes is crucial in maintaining the integrity and stability of the genome. Mutations or alterations in these genes can lead to their malfunctioning, resulting in uncontrolled cell growth and the development of cancer. When functioning normally, antioncogenes exert their tumor-suppressive effects by inhibiting the proliferation of cells, promoting programmed cell death (apoptosis), or repairing damaged DNA. They actively monitor and regulate various cell cycle checkpoints to prevent the growth of abnormal cells.
Some well-known examples of antioncogenes include the TP53 (p53) gene, BRCA1 and BRCA2 genes, PTEN gene, and the RB1 gene. Mutations or inactivation of these genes have been linked to the development of various cancers, such as breast, colon, and ovarian cancer.
The study of antioncogenes plays a significant role in cancer research and treatment. Understanding the function and mechanism of these genes helps in identifying potential therapeutic targets for cancer treatment as well as developing diagnostic tools for early detection of cancer.
Common Misspellings for ANTIONCOGENE
- zntioncogene
- sntioncogene
- wntioncogene
- qntioncogene
- abtioncogene
- amtioncogene
- ajtioncogene
- ahtioncogene
- anrioncogene
- anfioncogene
- angioncogene
- anyioncogene
- an6ioncogene
- an5ioncogene
- antuoncogene
- antjoncogene
- antkoncogene
- antooncogene
- ant9oncogene
- ant8oncogene
Etymology of ANTIONCOGENE
The word "antioncogene" is derived from two components: "anti-" and "oncogene".
1. "Anti-" is a prefix derived from the Greek word "antí", meaning "against" or "opposite". It is used to indicate opposition, resistance, or negation.
2. "Oncogene" is a term formed by the combination of "onco-" and "-gene". The prefix "onco-" is derived from the Greek word "onkos", meaning "mass" or "bulk", and it is typically used to denote something related to tumors or cancer. The suffix "-gene" stems from the Greek word "genos", meaning "birth" or "origin", and it commonly signifies a gene or a unit of heredity.
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