TROPANE Meaning and
Definition
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Tropane refers to a bicyclic organic compound that consists of a saturated six-membered ring fused to a five-membered ring. It belongs to the class of alkaloids and is derived from a modified form of the tropane skeleton. Tropanes are well-known for their diverse variety of pharmacological activities and are widely used in medicinal chemistry and drug development.
The tropane structure is characterized by the presence of a nitrogen atom in the bridging chain between the two rings, which imparts basicity to the compound. This basic nature makes tropanes capable of forming salts with acids, thereby enhancing their stability and solubility.
Due to their unique structural features, tropanes exhibit a myriad of biological activities. They are often found in plant species of the Solanaceae family, where they serve as defense compounds against herbivores. Tropane alkaloids are also known to possess various pharmacological properties, including analgesic, anesthetic, bronchodilatory, and anticholinergic effects.
In addition to their natural occurrence, tropane alkaloids are synthesized through chemical methods to produce pharmaceutical drugs. Among the most notable examples is atropine, a tropane alkaloid derived from plants such as Atropa belladonna, which acts as an anticholinergic medication. Other tropane-containing drugs include scopolamine, used in the treatment of motion sickness, and cocaine, which possesses potent stimulant and anesthetic properties.
Overall, tropane compounds represent an important class of chemical entities that have significant implications in the fields of pharmacology, medicine, and drug discovery.
Common Misspellings for TROPANE
- rropane
- fropane
- gropane
- yropane
- 6ropane
- 5ropane
- teopane
- tdopane
- tfopane
- ttopane
- t5opane
- t4opane
- trkpane
- trlpane
- trppane
- tr0pane
- tr9pane
- trooane
- tro0ane
- tropzne
Etymology of TROPANE
The word "tropane" derives from the chemical compound "tropa(n)e alkaloids". It is named after Atropa belladonna, commonly known as belladonna or deadly nightshade, which belongs to the Solanaceae family of plants. These plants contain tropane alkaloids, including atropine and scopolamine, which have powerful pharmacological properties. The name "Atropa" originates from Greek mythology, referring to Atropos, one of the three Fates who determined the destiny of individuals and cut the thread of life. This name was attributed to the plant due to its toxic and lethal properties. Hence, the term "tropane" is associated with the presence of these alkaloids in the belladonna plant and other related species.
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