SILDENAFIL Meaning and
Definition
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Sildenafil is a medicinal compound primarily used in the management of erectile dysfunction (ED). It is classified as a phosphodiesterase type 5 (PDE5) inhibitor, which means it functions by enhancing the effects of nitric oxide, a natural chemical released during sexual stimulation. Nitric oxide facilitates the relaxation of smooth muscles in the penis, promoting increased blood flow and subsequently leading to an erection. Sildenafil acts by blocking the action of the enzyme phosphodiesterase 5, preventing it from breaking down the cyclic guanosine monophosphate (cGMP) responsible for maintaining an erection.
In addition to its usage for ED, sildenafil also finds application in treating certain other medical conditions. It is utilized to address pulmonary arterial hypertension (PAH), a condition characterized by high blood pressure in the arteries that supply the lungs, leading to breathing difficulties and fatigue. Sildenafil works by improving the dilation of blood vessels, thus reducing the workload on the heart and enhancing exercise capacity in PAH patients.
Sildenafil is typically available as an oral tablet and is most commonly marketed under the brand name Viagra. It is typically taken as needed, about 30 minutes to an hour before anticipated sexual activity, with a recommended dosage prescribed by a healthcare professional. However, it is crucial to note that Sildenafil should not be consumed without medical guidance, as it can interact with certain medications or pose risks to individuals with specific underlying medical conditions such as heart disease.
Common Misspellings for SILDENAFIL
- aildenafil
- zildenafil
- xildenafil
- dildenafil
- eildenafil
- wildenafil
- suldenafil
- sjldenafil
- skldenafil
- soldenafil
- s9ldenafil
- s8ldenafil
- sikdenafil
- sipdenafil
- siodenafil
- silsenafil
- silxenafil
- silcenafil
- silfenafil
Etymology of SILDENAFIL
The word sildenafil originates from the combination of two sources: the prefix sili- and the suffix -denafil.
The prefix sili- is derived from the chemical name of the compound, which is sildenafil citrate. The name of the compound was formed by modifying the chemical name of its predecessor, thiomethisosildenafil. This modification replaced the thio- prefix with sili-.
The suffix -denafil is a common suffix used in the names of drugs that belong to the phosphodiesterase type 5 inhibitor (PDE-5 inhibitor) class. This class of drugs is used to treat erectile dysfunction, and many of them end with the -denafil suffix. The suffix was likely chosen for its style and similarity to other drugs in the same class, such as vardenafil and tadalafil.
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